Gathering the record
Relay is organizing the evidence and source boundaries.
Synthetic tetrapeptide
An experimental peptide marketed around hormone-related claims. It is not an approved hormone treatment.
Evidence is explained by question. Dosing references show their own check dates.
60-second overview
Why people look into it, what studies found, and what is still unknown.
Educational information only. Evidence reviewed through July 31, 2026. Published studies, sponsor announcements, and trials without results are labeled separately. Evidence gaps apply to the specific finding beside them.
Research questions
Each label shows how much evidence supports that question.
What studies show
Human-derived cells have been studied in vitro; no controlled human administration trial was located.
This is the strongest human-evidence boundary in the current record.
Mechanistic findings explain biological plausibility; they do not establish a human outcome.
Relay keeps this uncertainty visible rather than converting it into a prediction.
The safety snapshot reflects the studied record and its limitations.
Regulatory and identity status determine how the evidence should be interpreted.
Risks & unknowns
Current evidence cannot yet resolve: Human pharmacokinetics, endocrine outcomes, reproductive effects, off-target growth signaling, and longer-term safety.
No direct evidenceAn absence of adequate evidence is not evidence of benefit, harm, or equivalence.
Open sourceThe available information does not reliably show how often particular side effects occur.
Evidence boundaryUnder-detected or under-reported events must not be described as rare.
Relay has not verified which side effects led people to stop treatment in studies.
Evidence boundaryThis is an evidence gap, not proof that discontinuations did not occur.
Relay has not verified a compound-specific warning summary for this profile.
Evidence boundaryPreclinical; no FDA-approved Testagen/KEDG product. Human pharmacokinetics, endocrine outcomes, reproductive effects, off-target growth signaling, and longer-term safety.
This profile does not contain verified, product-specific emergency instructions.
Evidence boundaryRelay does not infer emergency guidance from study discontinuations, mechanism, or incomplete adverse-event reporting.
Dosing references
Each table labels its source and applies only to the named route, product, or study. An online example or community report is not an approved dose.
The reviewed molecular and preclinical findings do not establish an administered-human testosterone or thyroid-treatment schedule.
What would fill this gap: A direct human study of the exact synthetic Testagen peptide.
Dosing review checked Oct 20, 2026. Additional sources are available below.No route-specific preparation instructions were verified. A different route or product does not supply them.
Starting dose: the amount used at the beginning of the named label schedule or trial.
Maintenance: the ongoing amount described by that product label.
Trial target: the amount assigned to a study group. Different groups may stop increasing at different targets.
Published research exposed cultured cells to fluorescently labeled KEDG and tracked whether the peptide entered and localized within the cells.
Population: No directly studied human population was verified for this identity.
Design: Cell-culture uptake study
Mechanisms
KEDG can enter cultured cells and has been associated with gene-expression changes in experimental systems. These findings do not establish endocrine restoration in humans.
A plausible mechanism can explain why a study was attempted. It does not prove that the compound improves a human outcome.
No single validated target is established in the current record.
Research reference
A reference for the studies, populations, and routes behind this profile.
Laboratory and animal evidence; no controlled administered-human outcome study located.
Research depth describes how large and mature the overall record is. It does not tell you whether the results were positive.
Human pharmacokinetics, endocrine outcomes, reproductive effects, off-target growth signaling, and longer-term safety.
Confidence describes how reliable and consistent the conclusions are. It can be high for one outcome and low for another.
The strongest evidence type shows what the best-supported conclusions are actually based on.
Human findings are more directly relevant than animal or laboratory results, but they still apply only to the populations and outcomes studied.
Route-specific record
These are exposures used in cited research for a specific route and population—not an instruction for an individual.
Half-life describes how long it takes the measured amount in the body to fall by half. It is not a dosing recommendation.
Evidence can change by administration method. Findings from one route should not automatically be applied to another.
Evidence boundary: Participants were not treated, and cell entry is not a clinical outcome. The study cannot establish human absorption, pituitary benefit, endocrine effects, reproductive safety, or long-term risk. Amounts shown describe cited research exposure—not a dosage recommendation.
Studies
Study arms are reported for transparency. They describe what researchers did in a defined record and do not transfer across identities, routes, formulations, or populations.
A later trial phase can ask a more mature question, but it does not guarantee a positive result, regulatory approval, or relevance outside the studied population.
Cell-culture uptake study
Population not stated.
Fluorescently labeled KEDG entered cultured cells and localized to cellular compartments.
Study administration: Not stated in the current record.
Limitations: Cell penetration does not establish a therapeutic outcome.
Animal and laboratory study
Rodents and cultured cells
Endpoints were not fully described in the current record.
Animal and cell studies reported changes in pituitary-related markers.
Study administration: Not stated in the current record.
Limitations: Preclinical marker changes do not establish human endocrine benefit.
Community
Built by the community
Every structured report adds useful context about research setup, outcomes, and unwanted effects as the community dataset grows.
Publicly anonymous by default. Your account keeps reports editable and helps reduce duplicate submissions.Sources
PMID 22117547
PMID 20731122